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Cardiovascular Endocrinology: Shared Pathways and Clinical by Ronald Tamler, Derek LeRoith (auth.), Vivian A. Fonseca

By Ronald Tamler, Derek LeRoith (auth.), Vivian A. Fonseca (eds.)

Over the previous few many years, heart problems and diabetes have emerged as significant public illnesses, either as specified scientific entities and as comorbid stipulations. therefore, the fields of vascular biology and endocrinology are operating extra heavily now than ever earlier than. With chapters by means of well known specialists, Cardiovascular Endocrinology: Shared Pathways and scientific Crossroads emphasizes the massive physiological interrelationships and scientific correlations among the specialties of cardiovascular medication and endocrinology. providing a wealth of knowledge, Cardiovascular Endocrinology: Shared Pathways and medical Crossroads provides quite a number insights, together with a unique view of the hormonal law of the vascular approach and the disruption of the nitric oxide signaling process. It additionally addresses the function of fatty acids and cytokines within the improvement of this challenge. Importantly, this designated name additionally offers a cutting-edge replace at the significance of different hormones reminiscent of thyroid hormone and steroids, in addition to the pathophysiology of heart problems and controversies surrounding using hormone substitute treatment. In all, Cardiovascular Endocrinology: Shared Pathways and medical Crossroads is a first-of-its-kind name that discusses and summarizes very important medical issues in cardiology and endocrinology. It deals clinicians and researchers a major source for navigating the more and more interrelated pathways of cardiovascular and endocrinologic problems. The authors talk about a number very important concerns from epidemiology to bench study to translation of this examine to medical perform.

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Extra resources for Cardiovascular Endocrinology: Shared Pathways and Clinical Crossroads

Sample text

The NO generated within vascular endothelial cells, diffuses into vascular smooth muscle, stimulates guanylate cyclase to generate cGMP that eventually induces vasodilation. This process is termed endothelium-dependent vasodilation. However, clinically used nitrosodonors, such as nitroglycerin and sodium nitroprusside, can directly release NO or release NO following cleavage from an enzymatic reaction. The NO that is released from these donors acts via the same signaling pathway as endogenously produced NO to produce relaxation of vascular smooth muscle and vasodilation.

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